Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection

Title:

Cryografts implantation in human circulation would ensure a physiological transition in the arterial wall energetics, damping and wave reflection

Creator:

Bia, Daniel, Barra, J. G., Armentano, R. L., Zócalo, Y., Pérez, H., Saldías, M., Álvarez, I., and Cabrera Fischer, E. I.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6e8e4f50-74c0-4bcd-839c-b981891c47af
uuid:6e8e4f50-74c0-4bcd-839c-b981891c47af
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, viskoelasticita, physiology, viscoelasticity, arterial wall, cryopreservation, buffer function, conduit function, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Each artery conduces blood (conduit function, CF) and smoothes out the pulsatility (buffering function, BF), while keeping its wall protected against the high oscillations of the pulse waves (damping function, ξ). These functions depend on each segment viscoelasticity and capability to store and dissipate energy. When a graft/prosthesis is implanted, the physiological gradual transition in the viscoelasticity and functionality of adjacent arterial segments is disrupted. It remains to be elucidated if the cryografts would allow keeping the physiological biomechanical transition. The aim of this study was to evaluate the cryografts capability to reproduce the functional, energetic and reflection properties of patients’ arteries and fresh homografts. Common carotid’s pressure, diameter and wall-thickness were recorded in vivo (15 patients) and in vitro (15 cryografts and 15 fresh homografts from donors). Calculus: elastic (Epd) and viscous (Vpd) indexes, CF, BF, dissipated (WD) and stored (WPS) energy and ξ. The graft-patient’s artery matching was evaluated using the reflection coefficient (Γ) and reflected power (WΓ). Cryografts did not show differences in Epd, Vpd, BF, CF, WD, WPS, and ξ, in respect to fresh homografts and patients’ arteries, ensuring a reduced Γ and WΓ. Cryografts could be considered as alternatives in arterial reconstructions since they ensure the gradual transition of patients’ arteries biomechanical and functional behavior., D. Bia, J. G. Barra, R. L. Armentano, Y. Zócalo, H. Pérez, M. Saldíaz, I. Álvarez, E. I. Cabrera Fischer., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2008 Volume:57 | Number:3

Harvested from:

CDK

Metadata only:

false