Midazolam and its effect on vital signs and behavior in children under conscious sedation in dentistry

Title:

Midazolam and its effect on vital signs and behavior in children under conscious sedation in dentistry

Creator:

Vašáková, Jana, Dušková, Jana, Lunackova, Jitka, Drapalova, Klara, Zuzankova, Lucie, Stárka, Luboslav, Dušková, Michaela, and Broukal, Zdeněk

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:6a28abf4-803e-44bf-b332-f1e5997c5131
uuid:6a28abf4-803e-44bf-b332-f1e5997c5131
issn:0862-8408
doi:10.33549/physiolres.934511

Subject:

děti, midazolam, children, conscious sedation, vital signs, dentistry, 14, and 612

Type:

model:article and TEXT

Format:

počítač and online zdroj

Description:

Midazolam is a short acting sedative with small number of adverse effects. Administered orally, it is currently the most common form of conscious sedation in children. The objective of this paper is to describe effect of midazolam administered to children during dental treatment on their vital signs, and to monitor changes in children’s behavior. We described values of vital signs and behavior in 418 sedations conducted in 272 children between 1-12 years of age. To achieve the following results, we used data from 272 all first-time sedations. After administration of midazolam arterial blood pressure and blood oxygen saturation decreased by values which were not clinically significant. The heart rate increased, with values staying within the limits of physiological range. The speed of onset of midazolam’s clinical effects depends on age and dose. The lower age and dose correlated with the higher behavior score. The effectiveness of midazolam treatment is 97.8 %. Unwillingness of child to receive midazolam is predictor for disruptive behavior during sedation. 1.8 % of all sedation cases showed paradoxical reactions. The administration of midazolam in dose of 0.5 mg per 1 kg of child’s body weight is safe and could be recommended for dental treatment in pediatric dentistry., Jana Vasakova, Jana Duskova, Jitka Lunackova, Klara Drapalova, Lucie Zuzankova, Luboslav Starka, Michaela Duskova, Zdenek Broukal., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

S305-S314

Source:

Physiological research | 2020 Volume:69 | Number:Supplement 2

Harvested from:

CDK

Metadata only:

false