Complement fixing antibody production in thymectomized Oncorhynchus mykiss, vaccinated against or infected with the pathogenic haemoflagellate Cryptobia salmositica

Title:

Complement fixing antibody production in thymectomized Oncorhynchus mykiss, vaccinated against or infected with the pathogenic haemoflagellate Cryptobia salmositica

Creator:

Feng, Shujuan and Woo, Patrick T. K.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:5dca7acf-38ce-4be1-9437-5d628be0fd75
uuid:5dca7acf-38ce-4be1-9437-5d628be0fd75
urnnbn:urn:nbn:cz:aba007-000dnh

Subject:

Cryptobia salmositica, rainbow trout, complement fixing antibody, thymectomy, and vaccination

Type:

model:internalpart and TEXT

Format:

print

Description:

Short-term thymectomized (two months after thymectomy) adult rainbow trout, Oncorhynchus mykiss (Walbaum) infected with the flagellate Cryptobia salmositica Katz, 1951 responded well during primary infection with C. salmositica and recovered fish also showed secondary response (rapid production of complement fixing antibody after homologous challenge) five months after recovery. Complement fixing antibody was detected during primary and secondary responses and the titres of complement fixing antibody in thymectomized fish were significantly lower than those in infected intact fish. The parasitaemia in thymectomized infected fish was significantly lower than in intact infected fish. Both recovered thymectomized fish and intact fish were protected from cryptobiosis when they were challenged. Similarly, long-term thymectomized fish (nine months after thymectomy) vaccinated with an attenuated strain of C. salmositica were protected from cryptobiosis. There were no significant difference (P > 0.05) in parasitaemia, packed cell volume and complement fixing antibody titres between vaccinated/challenged thymectomized and vaccinated/challenged intact fish. Hence, thymectomy in adult rainbow trout did not decrease the detectable complement fixing antibody against C. salmositica in long-term thymectomized fish but reduced the detectable protective antibody in short-term thymectomized fish.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Coverage:

188-194 and 30-36

Source:

Folia parasitologica | 1997 Volume:44 | Number:3

Harvested from:

CDK

Metadata only:

false