One-year results from cryopreserved mitral allograft transplantation into the tricuspid position in a sheep experimental model

Title:

One-year results from cryopreserved mitral allograft transplantation into the tricuspid position in a sheep experimental model

Creator:

Aleš Mokráček, Canadyova, J., Simunkova, Z., Fiala, R., Hmirak, M., Sulda, M., Jan Burkert, Tintera, J., Petr Kobylka, and Jaroslav Špatenka

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:593d37f6-477e-4312-8467-4100633cad65
uuid:593d37f6-477e-4312-8467-4100633cad65
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie, physiology, mitral allograft, tricuspid valve replacement, cryopreservation, sheep experimental model, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Mitral allografts are still used only exceptionally in the mitral or tricuspid position. The main indication remains infectious endocarditis of atrioventricular valves for its flexibility and low risk of infection. The aim of our study was to evaluate 1-year results of mitral allografts transplantation into the tricuspid position in a sheep model. Mitral allografts were processed, cryopreserved, a nd transplanted into the tricuspid position anatomically (Group I - 11 animals) or antianatomically (Group II - 8 animals). All survivors (4 from Group I, and 3 from Group II) were checked at 3, 6, and 12 months by echocardiography with the exception of one survivor from Group II (which was examinated only visually). Examination throughout follow-up included for mitral allograft regurgitation and annuli dilatation. At postmortem, the papillary muscles were healed and firmly anchored to the right ventricular wall in all subjects. Transventricular fixation of the papillary muscles with buttressed sutures was proven to be a stable, reproducible, and safe method for anchoring mitral allograft leaflets. There were no significant differences between the two implan tation methods. Annulus support of mitral allografts might be very useful in this type of operation and could prevent annular dilatation., A. Mokracek, J. Canadyova, Z. Simunkova, R. Fiala, M. Hmirak, M. Sulda, J. Burkert, J. Tintera, P. Kobylka, J. Spatenka., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:6

Harvested from:

CDK

Metadata only:

false