Immunohistochemical demonstration of blood vessels alpha-actin down-regulation in LPS-treated pregnant mice

Title:

Immunohistochemical demonstration of blood vessels alpha-actin down-regulation in LPS-treated pregnant mice

Creator:

Zavan, B., Giusti-Paiva, A., Soncini, R., Do Amarante-Paffaro, A. M., and Paffaro, V. A.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:54c62b9d-b1fb-4009-b5b9-25e76cec14f2
uuid:54c62b9d-b1fb-4009-b5b9-25e76cec14f2

Subject:

Fyziologie člověka a srovnávací fyziologie, fyziologie člověka, human physiology, alpha-actin, blood vessels, uterus, 14, and 612

Type:

article, články, model:article, and TEXT

Description:

Lipopolysaccharide (LPS), produced by gram-negative bacteria, mediates vasodilatation, changing the action of contractile smooth muscle by increasing expression of nitric oxide synthase and prostaglandin. For the first time we demonstrate, by immunohistochemical methods, that administration of LPS to pregnant mice causes α-actin-mediated down-regulation of contractile filaments in uterine blood vessels, thereby potentially increasing vessels permeability, blood supply, and immune cells homing to this environment, culminating in the reestablishment of uterine homeostasis., B. Zavan ... [et al.]., and Obsahuje seznam literatury

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2012 Volume:61 | Number:5

Harvested from:

CDK

Metadata only:

false