Intrauterine undernutrition and programming as a new risk of cardiovascular disease in later life

Title:

Intrauterine undernutrition and programming as a new risk of cardiovascular disease in later life

Creator:

Peter Szitányi, Janda, J., and Rudolf Poledne

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:502e476e-aa1f-4fdc-8a1b-f5627958fe1f
uuid:502e476e-aa1f-4fdc-8a1b-f5627958fe1f
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, programování, ateroskleróza, kardiovaskulární nemoci, programming, atherosclerosis, cardiovascular diseases, intrauterine undernutrition, low birth weight, risk factors of cardiovascular disease, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

It is believed that atherogenesis is a multifactorial process, which could already start in utero. Development of atherosclerosis progresses over decades and leads to the cardiovascular morbidity and mortality in adulthood. At present, we have no exact explanation for all the risk factors acting in the pathogenesis of atherosclerosis. This review should provide an overview about the possible role of intrauterine undernutrition in the development of risk factors for cardiovascular disease. Intrauterine undernutrition leads to changes in fetal growth and metabolism and programs later development of some of these risk factors. A number of experimental and human studies indicates that hypertension as well as impaired cholesterol and glucose metabolism are affected by intrauterine growth. Intrauterine undernutrition plays an important role and acts synergistically with numerous genetic and environmental factors in the development of atherosclerosis. There is evidence that undernutrition of the fetus has permanent effects on the health status of human individuals., P. Szitányi, J. Janda, R. Poledne., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:4

Harvested from:

CDK

Metadata only:

false