Three months of regular aerobic exercise in patients with obesity improve systemic subclinical inflammation without major influence on blood pressure and endocrine production of subcutaneous fat

Title:

Three months of regular aerobic exercise in patients with obesity improve systemic subclinical inflammation without major influence on blood pressure and endocrine production of subcutaneous fat

Creator:

Trachta, P., Drápalová, J., Petra Kaválková, Toušková, V., Cinkajzlová, A., Zdeňka Lacinová, Martin Matoulek, Tomáš Zelinka, Jiří Widimský, Miloš Mráz, and Martin Haluzík

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:414ab269-1de7-401f-8dba-8721917bf912
uuid:414ab269-1de7-401f-8dba-8721917bf912
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, obezita, obesity, physical activity, adipose tissue, proinflammatory factors, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The aim of our study was to explore the effects of regular aerobic exercise on anthropome tric, biochemical and hormonal parameters and mRNA expression of selected factors involved in metabolic regulations in subcutaneous adipose tissue of patients with obesity. Fifteen obese wome n with arterial hypertension underwent a three-month exercise program consisting of 30 min of aerobic exercise 3 times a we ek. Fifteen healthy lean women with no intervention served as a control group. Obese group underwent anthropometric measurements, blood sampling, subcutaneous adipose tissue (SCAT) biopsy and 24-h blood pressure monitoring at baseline and after three months of exercise, while control group was examined only once. At baseline, obese group had increased SCAT expression of proinflammatory cytokines and adipokines relative to control group. Three months of regular exercise improved anthropometric parameters, decreased CRP, blood glucose and HOMA-IR, while having no significant effect on lipid profile and blood pressure. Gene expressions in SCAT were not affected by physical activity with the exce ption of increased aquaporin-3 mRNA expression. We conclude that three months of regular exercise decrease systemic subc linical inflammation with only minor influence on the blood pressure and the endocrine function of subcutaneous fat., P. Trachta, J. Drápalová, P. Kaválková, V. Toušková, A. Cinkajzlová, Z. Lacinová, M. Matoulek, T. Zelinka, J. Widimský Jr., M. Mráz, M. Haluzík., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2014 Volume:63 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false