Hormonal and bone parameters in pubertal girls

Title:

Hormonal and bone parameters in pubertal girls

Creator:

Veronika Cirmanová, Ivana Žofková, Petr Kasalický, Věra Lánská, Milan Bayer, Luboslav Stárka, and Radmila Kantcheva

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:4012f1fa-5348-41f6-9979-187f49ac13bc
uuid:4012f1fa-5348-41f6-9979-187f49ac13bc
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, kosti, puberta, leptin, melatonin, bones, puberty, IGF-1, serotonin, 14, and 612

Type:

article, text, články, journal articles, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Here we analyzed associations between muscles mass, total bone mineral content (BMC), lumbar spine bone density (BMD L1-L4) and serum or urine hormones in healthy peripubertal girls. Total BMC and areal BMD L1-L4, muscle mass and fat were measured by dual-energy X-ray absorptiometry (DXA). Muscle force (N) was estimated by a dynamometer. Circulating estradiol, folliclestimulating hormone (FSH), luteinizing hormone (LH), 25-hydroxy vitamin D, parathyroid hormone (PTH), insulin-like growth factor 1 (IGF-1), leptin, osteocalcin, bone isoenzyme of alkaline phosphatase (bALP) and total calcium and phosphorus were quantified as the nocturnal melatonin and serotonin urinary excretion. Partial correlations adjusted for height, Tanner score and physical activity confirmed positive relationships between BMC or BMD L1-L4 (Z-score) and lean mass or fat. Furthermore, positive relationship was observed between BMC or BMD L1-L4 (Z-score) and serum leptin. After adjustment for Tanner score and physical activity, positive associations were observed between lean mass and IGF-1, leptin levels or muscle force. We proved positive relationships between bone mass and serum leptin in peripubertal girls., V. Cirmanova, I. Zofkova, P. Kasalicky, V. Lanska, M. Bayer, L. Starka, R. Kanceva., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2017 Volume:66 | Number:Suppl 3

Harvested from:

CDK

Metadata only:

false