Excitability changes of cortical neurons during the postnatal period in rats exposed to prenatal hypobaric hypoxia

Title:

Excitability changes of cortical neurons during the postnatal period in rats exposed to prenatal hypobaric hypoxia

Creator:

Dana Marešová, Valkounová, I., Kateřina Jandová, Jana Bortelová, and Stanislav Trojan

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:3601052b-9c02-4921-bc8d-56168204294c
uuid:3601052b-9c02-4921-bc8d-56168204294c
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, hypoxie, hypoxia, development, excitability of neurons, rats, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Pregnant rats were exposed to intermittent hypobaric hypoxia (at a simulated altitude of 7000 m or 5000 m) and the excitability of cortical neurons of their pups was tested. Stimulation of the sensorimotor cortex of rats prenatally exposed to hypoxia shortened the duration of cortical afterdischarges in 12-day-old rats, but did not change the excitability in 25-day-old animals. Shortening of the first afterdischarge in 35-day-old rats but the prolongation of the first afterdischarge in adult rats (as compared to the duration of cortical afterdischarges in rats not exposed to prenatal hypoxia) were registered. The possible mechanisms of different excitability of cortical neurons in rats prenatally exposed to hypobaric hypoxia are discussed., D. Marešová, I. Valkounová, K. Jandová, J. Bortelová, S. Trojan., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2001 Volume:50 | Number:2

Harvested from:

CDK

Metadata only:

false