Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial

Title:

Theta burst stimulation in the treatment of chronic orofacial pain: a randomized controlled trial

Creator:

Kohútová, B., Fricová, J., Klírová, M., Novák, T., and Rokyta, R.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:343f9a27-a41c-4773-8e3d-d77ee275b538
uuid:343f9a27-a41c-4773-8e3d-d77ee275b538

Subject:

repetitive transcranial magnetic stimulation, theta burst stimulation, pain, and analgesic effect

Type:

article, model:article, and TEXT

Description:

Theta burst stimulation (TBS) is a modified form of highfrequency repetitive transcranial magnetic stimulation (rTMS) with promising effect in chronic pain. The aim of our doubleblind, sham-controlled, parallel-group, randomized study was to assess an efficacy of intermittent TBS (iTBS) in the treatment of patients with chronic orofacial pain. Nineteen patients (twelve females) with chronic orofacial pain were prospectively included and randomly assigned to single session of an active (iTBS) or sham (intermediate TBS; imTBS) stimulation delivered to the primary motor cortex (M1) contralateral to painful side. The primary outcome was pain relief assessed using a visual analogue scale (VAS) after stimulation and at the end of two-week followup. The secondary outcomes were changes in the quantitative sensory testing (QST). QST set the threshold for thermal and tactile (touch) sensation in the affected facial area. Intermittent TBS, compared with the sham, showed significant improvement in VAS after stimulation, but not at the end of two-week followup. Regarding the secondary outcomes (QST), we failed to find any significant difference between iTBS and sham. Our findings demonstrate that iTBS of M1 transiently provides transient and modest subjective pain relief in chronic orofacial pain.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2017 Volume:66 | Number:6

Harvested from:

CDK

Metadata only:

false