Regulation of myosin expression in developing and regenerating extrafusal and intrafusal muscle fibers with special emphasis on the role of thyroid hormones

Title:

Regulation of myosin expression in developing and regenerating extrafusal and intrafusal muscle fibers with special emphasis on the role of thyroid hormones

Creator:

Tomáš Soukup and Jirmanová, I.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:296206d9-c805-48e6-840b-e15aa77495b9
uuid:296206d9-c805-48e6-840b-e15aa77495b9
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, hormony štítné žlázy, thyroid hormones, myosin heavy chains, myofibrillar proteins, muscle cell lineages, muscle innervation, muscle fiber types, muscle spindles, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Expression of the muscle phenotype is the result of interaction between intrinsic and extrinsic factors, the latter including innervation, mechanical influences and hormonal signals. This minireview summarizes some of the current knowledge regarding the regulation of myosin heavy chain (MHC) isoform transitions during muscle development and regeneration. It describes the role of genetic factors, neural and mechanical influences and it focuses on the contribution of thyroid hormones to the differentiation of muscle fiber phenotypes as shown by the regulation of the expression of MHC isoforms and development of myofibrillar ATPase activity. Finally, it shortly summarizes results regarding the differentiation of MHC isoforms in regenerated muscle fibers of the graft after heterochronous isotransplantation in rats with different thyroid status., T. Soukup, I. Jirmanová., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2000 Volume:49 | Number:6

Harvested from:

CDK

Metadata only:

false