Hepatoprotective effect of rooibos tea (Aspalathus Linearis) on CCl4-induced liver damage in rats

Title:

Hepatoprotective effect of rooibos tea (Aspalathus Linearis) on CCl4-induced liver damage in rats

Creator:

Oľga Uličná, Greksák, M., Vančová, O., Zlatoš, L., Štefan Galbavý, Peter Božek, and Nakano, M.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:236bf02f-d003-4c3d-ab30-0a3353858726
uuid:236bf02f-d003-4c3d-ab30-0a3353858726
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, Aspalathus linearis, rooibos, rooibos tea, N-acetyl-L-cysteine, hepatoprotective activity, CCl4-induced cirrhosis, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Hepatoprotective properties of rooibos tea (Aspalathus linearis) were investigated in a rat model of liver injury induced by carbon tetrachloride (CCl4). Rooibos tea, like N-acetyl-L-cysteine which was used for the comparison, showed histological regression of steatosis and cirrhosis in the liver tissue with a significant inhibition of the increase of liver tissue concentrations of malondialdehyde, triacylglycerols and cholesterol. Simultaneously, rooibos tea significantly suppressed mainly the increase in plasma activities of aminotransferases (ALT, AST), alkaline phosphatase and billirubin concentrations, which are considered as markers of liver functional state. The antifibrotic effect in the experimental model of hepatic cirrhosis of rats suggests the use of rooibos tea as a plant hepatoprotector in the diet of patients with hepatopathies., O. Uličná, M. Greksák, O. Vančová, L. Zlatoš, Š. Galbavý, P. Božek, M. Nakano., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2003 Volume:52 | Number:4

Harvested from:

CDK

Metadata only:

false