Antioxidant Vitamin Levels Do Not Exhibit Negative Correlation with the Extent of Acute Myocardial Infarction

Title:

Antioxidant Vitamin Levels Do Not Exhibit Negative Correlation with the Extent of Acute Myocardial Infarction

Creator:

Mužáková, V., Vojtíšek, P., Meloun, M., Vaňková, R., Roušar, T., and Červinková, Z.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:148b5fac-3552-4e8a-bd98-a75449e62d03
uuid:148b5fac-3552-4e8a-bd98-a75449e62d03

Subject:

Antioxidant vitamins, α-Tocopherol, β-Carotene, Ascorbic acid, and Myocardial infarction

Type:

article, model:article, and TEXT

Description:

Serum levels of vitamin E (VE), β-carotene (BC) and vitamin C (VC) were determined in 50 patients with the first acute myocardial infarction (AMI) before starting thrombolytical treatment. VE and BC were determined by HPLC, VC spectrophotometrically. The reperfused patients were divided according to vitamin concentrations into four groups. The lowest quartile was compared with the rest of the studied population (VE: group with high (H) > 15.6 μM > group with low (L), BC: H > 0.07 μM > L, VC: H > 25 μM > L) in the following parameters: extent of myocardial damage (area under the curves of troponin I, CK-MB during 48 h), arrhythmia and congestive heart failure occurrence, size of ejection fraction, positivity of ventricular late potentials. No significant differences between groups H and L for either VE, BC or VC were found (P±0.05). As no correlation between serum concentrations of vitamins E, C and β-carotene and the extent and clinical course of AMI was found, the actual vitamin concentrations may be important for prevention of ischemic heart a disease, but they do not play a decisive role in the acute phase of myocardial infarction in humans.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2005 Volume:54 | Number:6

Harvested from:

CDK

Metadata only:

false