Gestational diabetes - metabolic risks of adult women with respect to birth weight

Title:

Gestational diabetes - metabolic risks of adult women with respect to birth weight

Creator:

Daniela Vejražková, Petra Lukášová, Markéta Vaňková, Olga Bradnová, Vacinová, G., Josef Včelák, Veronika Cirmanová, Kateřina Andělová, Hana Krejčí, and Běla Bendlová

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0fd25f8c-1d57-488a-9a45-537809315d19
uuid:0fd25f8c-1d57-488a-9a45-537809315d19
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, diabetes mellitus, gestational dabetes mellitus, birth weight, metabolic syndrome, glucose tolerance, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Metabolic disorders such as obesity, insulin resistance and other components of metabolic syndrome (MetS) are connected with birth weight. Low and high birth weight is associated with a higher risk of developing type 2 diabetes mellitus, the mechanism is not clear. In this study, we evaluated the association between birth weight and anthropometric as well as biochemical components of MetS in women with a history of gestational diabetes mellitus (GDM) in comparison with control women. In part of the GDM group, we re-evaluated metabolic changes over 5-8 years. Anthropometry, blood pressure, glucose metabolism during the 3-h oGTT, lipid profile, uric acid, thyroid hormones, and liver enzymes were assessed. From the analyzed components of MetS in adult women we proved the association of low birth weight (birth weight <25th percentile) with glucose processing, in particular among women with a history of GDM. Low birth weight GDM women revealed significantly higher postchallenge insulin secretion and lower peripheral insulin sensitivity. Re-examinations indicate this association persists long after delivery., D. Vejrazkova, P. Lukasova, M. Vankova, O. Bradnova, G. Vacinova, J. Vcelak, V. Cirmanova, K. Andelova, H. Krejci, B. Bendlova., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false