Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men

Title:

Effects of resistance training on arterial compliance and plasma endothelin-1 levels in healthy men

Creator:

Tagawa, K., Ra, S.-G., Maeda, S., Miyauchi, T., Sakai, S., Takekoshi, K., Yoshida, Y., Yoshikawa, T., and Kumagai, H

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0c31f72b-ae01-4d19-b43e-8b71805735ca
uuid:0c31f72b-ae01-4d19-b43e-8b71805735ca
issn:0862-8408

Subject:

fyziologie člověka, human physiology, Resistance training, Carotid arterial compliance, Vasoconstrictor, Young men, Endothelin, EDCF, 14, and 612

Type:

model:article and TEXT

Format:

print, bez média, and svazek

Description:

Arterial compliance (AC) is an index of the elasticity of large arteries. Endothelial dysfunction has been reported to result in reduced arterial compliance, which represents increased arterial stiffness. A reduction in AC is elicited by high-intensity resistance training, however the mechanisms are obscure. Because a single bout of resistance exercise causes a transient increase in circulating plasma endothelin-1 in humans, some vasoconstrictors may play a role in the mechanisms. The present study aimed to investigate whether resistance training-induced decrease in AC is associated with changes in circulating vasoconstrictors levels in young men. Young sedentary men were assigned to control (n=5) or training (n=9) groups. The training group performed four-week high-intensity resistance training (weight training exercise; three sessions/week). We measured AC and plasma levels of endothelin-1, angiotensin II, and norepinephrine before and after intervention. Resistance training significantly decreased AC, whereas the changes in plasma levels of neither endothelin-1, nor angiotensin II, nor norepinephrine were significantly different between the control and the training groups. Moreover, we found no significant correlations between changes in circulating plasma levels (endothelin-1, angiotensin II, and norepinephrine) and in the AC. Despite of no alteration of the resting circulating plasma levels (endothelin-1, etc.), we cannot exclude a possibility that the tissue/local concentrations of vasoconstrictors (endothelin-1, etc.) around the vessels might be increased and also involved in a reduction of AC in the training group. Taken together, the present results suggest that circulating vasoconstrictors (endothelin-1, etc.) in plasma are not involved in a reduction in AC by the resistance training., K. Tagawa, S.-G. Ra, H. Kumagai, T. Yoshikawa, Y. Yoshida, K. Takekoshi, S. Sakai, T. Miyauchi, S. Maeda., and Seznam literatury

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2018 Volume:67 | Number:Suppl 1

Harvested from:

CDK

Metadata only:

false