How hormones influence composition and physiological function of the brain-blood barrier

Title:

How hormones influence composition and physiological function of the brain-blood barrier

Creator:

Richard Hampl, Marie Bičíková, and Sosvorová, L.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:03ec6df2-0297-4a4d-834b-401ff602cc31
uuid:03ec6df2-0297-4a4d-834b-401ff602cc31
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, hematoencefalická bariéra, hormony, blood-brain barrier, hormones, tight junction proteins, paracellular way, protein transporters, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Hormones exert many actions in the brain. Their access and effects in the brain are regulated by the blood-brain barrier (BBB). Hormones as other substances may enter the brain and vice versa either by paracellular way requiring breaching tight junctions stitching the endothelial cells composing the BBB, or by passage through the cells (transcellular way). Hormones influence both ways through their receptors, both membrane and intracellular, present on/in the BBB. In the review the main examples are outlined how hormones influence the expression and function of proteins forming the tight junctions, as well as how they regulate expression and function of major protein transporters mediating transport of various substances including hormone themselves., R. Hampl, M. Bičíková, L. Sosvorová., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:Suppl 2

Harvested from:

CDK

Metadata only:

false