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| Description: |
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| Posttransplant lymphoproliferative disorder, chronic renal insufficiency, squamous cell carcinoma of the skin, anemia secondary to chronic renal insufficiency and chemotherapy, and hypertension. |
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| The patient is here for followup visit and chemotherapy. |
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| CHIEF COMPLAINT: |
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| The patient is here for followup visit and chemotherapy. |
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| DIAGNOSES: |
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| 1. Posttransplant lymphoproliferative disorder. |
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| 2. Chronic renal insufficiency. |
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| 3. Squamous cell carcinoma of the skin. |
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| 4. Anemia secondary to chronic renal insufficiency and chemotherapy. |
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| 5. Hypertension. |
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| HISTORY OF PRESENT ILLNESS: |
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| A 51-year-old white male diagnosed with PTLD in latter half of 2007. |
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| He presented with symptoms of increasing adenopathy, abdominal pain, weight loss, and anorexia. |
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| He did not seek medical attention immediately. |
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| He was finally hospitalized by the renal transplant service and underwent a lymph node biopsy in the groin, which showed diagnosis of large cell lymphoma. |
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| He was discussed at the hematopathology conference. |
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| Chemotherapy with rituximab plus cyclophosphamide, daunorubicin, vincristine, and prednisone was started. |
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| First cycle of chemotherapy was complicated by sepsis despite growth factor support. |
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| He also appeared to have become disoriented either secondary to sepsis or steroid therapy. |
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| The patient has received 5 cycles of chemotherapy to date. |
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| He did not keep his appointment for a PET scan after 3 cycles because he was not feeling well. |
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| His therapy has been interrupted for infection related to squamous cell cancer, skin surgery as well as complaints of chest infection. |
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| The patient is here for the sixth and final cycle of chemotherapy. |
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| He states he feels well. |
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| He denies any nausea, vomiting, cough, shortness of breath, chest pain or fatigue. |
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| He denies any tingling or numbness in his fingers. |
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| Review of systems is otherwise entirely negative. |
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| Performance status on the ECOG scale is 1 |
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| PHYSICAL EXAMINATION: |
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| VITAL SIGNS: |
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| He is afebrile. |
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| Blood pressure 161/80, pulse 65, weight 71.5 kg, which is essentially unchanged from his prior visit. |
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| There is mild pallor noted. |
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| There is no icterus, adenopathy or petechiae noted. |
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| CHEST: Clear to auscultation. |
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| CARDIOVASCULAR: S1 and S2 normal with regular rate and rhythm. |
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| Systolic flow murmur is best heard in the pulmonary area. |
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| ABDOMEN: Soft and nontender with no organomegaly. |
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| Renal transplant is noted in the right lower quadrant with a scar present. |
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| EXTREMITIES: Reveal no edema. |
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| LABORATORY DATA: |
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| CBC from today shows white count of 9.6 with a normal differential, ANC of 7400, hemoglobin 8.9, hematocrit 26.5 with an MCV of 109, and platelet count of 220,000. |
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| ASSESSMENT AND PLAN: |
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| 1. Diffuse large B-cell lymphoma following transplantation. |
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| The patient is to receive his sixth and final cycle of chemotherapy today. |
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| PET scan has been ordered to be done within 2 weeks. |
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| He will see me back for the visit in 3 weeks with CBC, CMP, and LDH. |
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| 2. Chronic renal insufficiency. |
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| 3. Anemia secondary to chronic renal failure and chemotherapy. |
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| He is to continue on his regimen of growth factor support. |
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| 4. Hypertension. |
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| This is elevated today because he held his meds because he is getting rituximab other than that this is well controlled. |
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| His CMP is pending from today. |
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| 5. Squamous cell carcinoma of the skin. |
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| The scalp is well healed. |
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| He still has an open wound on the right posterior aspect of his trunk. |
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| This has no active drainage, but it is yet to heal. |
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| This probably will heal by secondary intention once chemotherapy is finished. |
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| Prescription for prednisone as part of his chemotherapy has been given to him. |